She’s at the end of her rope.

　　她已经无计可施了。

　　解释：“at the end of one's rope”无计可施，山穷水尽

　　unable to endure, tolerate a condition or situation无法忍受某种状况或情形

　　例句：

　　The mother of the kidnapped child was at the end of her rope from worry when she received word that her son had been released unharmed.

　　消息传来，小孩已安全获释；此时这位被绑票的小孩的母亲已因为焦虑而陷于绝境。