The history of life on earth has been a history of interaction between living things and their surroundings. To a large extent, the physical form and the habits of the earth's vegetation and its animal life have been molded by the environment. Considering the whole span of earthly time, the opposite effect, in which life actually modifies its surroundings, has been relatively slight. Only in the present century has one species man acquired significant power to alter the nature of his world.

　　During the past quarter century this power has not only become increasingly great but it has changed in character. The most alarming of all man's assaults upon the environment is the contamination of air, earth, rivers, and sea with dangerous and even lethal materials. This pollution is for the most part irrecoverable. In this now universal contamination of the environment, chemicals are the sinister partners of radiation in changing the very nature of the world the very nature of its life. Chemicals sprayed on croplands or forests or gardens lie long in soil, entering into living organisms, passing from one to another in a chain of poisoning and death. Or they pass mysteriously by underground streams until they emerge and combine into new forms that kill vegetation, sicken cattle, and work unknown harm on those who drink from once pure wells. "Man can hardly even recognize the devils of his own creation," as a scientist has said.

　　It took hundreds of millions of years to produce the life that now inhabits the earth. Given time not in years but in millennia life adjusts, and a balance has been reached. But in the modern world there is no time.

　　The rapidity of change follows the impetuous pace of man rather than the deliberate pace of nature. Radiation is now the unnatural creation of man’s tampering with the atom. The chemicals are the synthetic5 creations of man's inventive mind, having no counterparts in nature.

　　To adjust to these chemicals would require not merely the years of a man's life but the life of generations. And even this, were it by some miracle possible, would be futile, for the new chemicals come from our laboratories in an endless stream; almost five hundred annually find their way into actual use in the United States alone. Among them are many that are used in man's war against nature. Since the mid 1940's over 200 basic chemicals have been created for use in killing insects, weeds, and other organisms described as "pests."

　　It is not my contention that chemical insecticides must never be used. I do contend that we have put poisonous and biologically potent chemicals indiscriminately into the hands of persons largely or wholly ignorant of their potentials for harm. We have subjected enormous numbers of people to contact with these poisons, without their consent and often without their knowledge. I contend, furthermore, that we have allowed these chemicals to be used with little or no advance investigation of their effect on soil, water, wildlife, and man himself. Future generations are unlikely to forgive our lack of concern for the integrity of the natural world that supports all life.