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儿童诵读困难 科学家发现相关基因
http://www.sina.com.cn 2005/03/21 18:01  国际在线

  A gene which is likely to be one of the causes of dyslexia in children has been discovered by researchers at Cardiff University.

  They believe the major finding will give researchers a better understanding of what causes the brain disorder which disrupts reading and writing skills.

  It is now hoped that follow-up research will also lead to the discovery of treatments which could help children susceptible to dyslexia.

  The discovery was made by a team from the Department of Psychological Medicine, Wales College of Medicine.

  They carried out analysis of 300 families from Wales and the West of England where at least one child suffered from the disorder.

  The research team led by Professor Julie Williams and Professor Michael O'Donovan will now continue their study in order to discover more about the gene called "KIAA0319".

  The research will focus on discovering exactly how the gene works within the brain to disrupt reading and writing skills.

  Professor Williams said: "This is a major breakthrough and the first study to identify one gene which contributes to susceptibility to the common form of dyslexia. We would like to thank all the parents and children who took part in the study and would extend a call to new volunteers to take part in this important research."

  The researchers want to hear from more families with at least one child who has dyslexia.

  Professor O'Donovan said: "The finding vindicates our optimism that a disorder as apparently complicated as impaired reading ability can be amenable to molecular genetic dissection." However, he added: "Much more remains to be done before the finding is translated into therapy. To tackle the genetic origins of disorders like dyslexia, both quality of assessment and sample size are crucial. We have the tools to take care of the latter, but we are entirely dependent on the altruism of the public in offering their time and DNA".

儿童诵读困难 科学家发现相关基因

  英国加的夫大学的科学家们日前发现了一种与儿童诵读困难(dyslexia)有关的基因,并希望在接下来的研究中,找到能够治疗这种病症的方法。

  据美国“每日科学”网站3月20日报道,这种基因被称为"KIAA0319",英国加的夫大学的科学家们认为它可能是导致儿童出现诵读困难的原因之一。研究者相信,这一发现可以让人们更好地了解是什么引起了大脑障碍,从而使孩子的读写能力受到破坏。

  在研究过程中,科学家们对威尔士和英格兰西部的300个家庭进行了分析研究,他们发现至少有1名儿童正在忍受诵读困难带来的不便。这个由朱莉-威廉姆斯教授和迈克尔-O'多诺万教授领导的研究小组目前正继续他们的研究工作,希望了解和"KIAA0319"基因有关的更多信息。威廉姆斯教授表示:“这是一个很大的突破,同时也是人们首次证实某种基因和一般的诵读困难具有紧密联系。”

  报道说,研究人员将把工作重点放在解读这种基因在大脑内部确切的作用机制,并希望通过深入的研究工作,发现针对诵读困难的治疗方法,从而帮助那些受这一病症影响的孩子们。

  诵读困难是一种学习障碍,症状是识别或理解书写文字的能力受到损伤。(文/王高山)




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